The Ticker

FDA panel rejects Aveo's cancer drug application

Aveo Pharmaceuticals shares tanked yesterday after the Cambridge-based biotechnology company said a U.S. Food and Drug Administration panel voted the former's application for its cancer drug tivozanib did not demonstrate a favorable benefit-to-risk evaluation for treating advanced renal cell carcinoma in a trial.

The FDA's review of the drug application is expected to be complete by July 28.

Hamilton Co. buys Boston block

The Hamilton Co. has acquired a 134-unit Boston apartment complex amid the Northeastern University campus for $52 million. Purchased from Boston Land Development, the property at 650 Columbus Ave. encompasses an entire block in Roxbury and also includes 33 condos and a 141-car garage.

Liberty Mutual earnings fall

Liberty Mutual Insurance's first-quarter earnings fell nearly 31 percent, due largely to a $130 million loss tied to Venezuela's recent devaluation of its currency. The company's net income fell by $141 million to $318 million for the three months that ended March 31.

Revenue climbed 3 percent to $9.14 billion from $8.88 billion in the same period of 2012.

Two Hub office buildings sold

TIAA-CREF has agreed to purchase 40 Broad St. for $105 million, and Deutsche Asset & Wealth Management topped rival bidders with its $21.4 million offer for 45 Milk St. Chicago-based Pearlmark Real Estate bought the 11-story, 290,000-square-foot Broad Street building for nearly $50 million in 2006. Anglo Irish Bank is the seller of the mostly vacant nine-story, 69,000-square-foot Milk Street building.

Billionaire joins Twittersphere

Berkshire Hathaway CEO Warren Buffett unveiled his own Twitter handle, @WarrenBuffett, during a speech yesterday. The 82-year-old's first tweet said simply, "Warren is in the house." By the end of the day, the billionaire had amassed followers in the tens of thousands.

TODAY

 The U.S. jobs report for April is released.

 David P. Bergers, left, acting deputy director of the Securities and Exchange Commission's Enforcement Division and director of the Boston Regional Office, is leaving the agency after 13 years of federal service. John T. Dugan will become the acting director of the Boston office.

 Aegerion Pharmaceuticals Inc. of Cambridge has appointed Anne M. VanLent to its board of directors. VanLent, who is currently the president of advisory firm AMV Advisors, will serve as chairwoman of the audit committee.

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